Dna Polymerase Klenow Fragment is a photograph by Laguna Design which was uploaded on May 1st, 2013.
Dna Polymerase Klenow Fragment
Klenow fragment of DNA polymerase I. Computer model showing the secondary (alpha-helices and beta-sheets) and primary (ball-and-stick) structures of... more
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Dna Polymerase Klenow Fragment
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Laguna Design
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Photograph
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Klenow fragment of DNA polymerase I. Computer model showing the secondary (alpha-helices and beta-sheets) and primary (ball-and-stick) structures of the Klenow, or large, fragment from DNA olymerase I. DNA polymerase synthesises a new DNA strand from a complementary template strand during DNA replication. This fragment retains this activity, and the ability to cleave nucleotides form the strand in the opposite direction to replication, but has lost the ability to cleave nucleotides in the same direction as replication. This allows the enzyme to be used in a number of research applications, including preparing radioactive DNA probes.
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May 1st, 2013
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