Transportation Photograph - Torcetrapib And Cholesterol #2 by Ramon Andrade 3dciencia

Torcetrapib And Cholesterol #2 is a photograph by Ramon Andrade 3dciencia which was uploaded on July 28th, 2016.

Torcetrapib And Cholesterol #2

Torcetrapib and cholesterol. Computer illustration showing the structure of a molecule of the cholesterol-lowering drug torcetrapib (green), bound to... more

by Ramon Andrade 3dciencia

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Title

Torcetrapib And Cholesterol #2

Artist

Ramon Andrade 3dciencia

Medium

Photograph

Description

Torcetrapib and cholesterol. Computer illustration showing the structure of a molecule of the cholesterol-lowering drug torcetrapib (green), bound to a cholesteryl ester transfer protein (CETP) and high-density lipoprotein (HDL, yellow) complex. Lipoproteins are the major carriers of cholesterol in the blood and are mainly composed of lipids. CETP, also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. Torcetrapib was being developed to treat high cholesterol levels (hypercholesterolemia) and to prevent cardiovascular disease. However, its development was stopped in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.

Uploaded

July 28th, 2016