Migraine Therapy And Cgrp Receptor #1 is a photograph by Juan Gaertner/science Photo Library which was uploaded on October 24th, 2019.
Migraine Therapy And Cgrp Receptor #1
Migraine therapy and CGRP receptor, illustration. Monoclonal antibodies (red) being used to block the calcitonin gene-related peptide (CGRP) receptor... more
Title
Migraine Therapy And Cgrp Receptor #1
Artist
Juan Gaertner/science Photo Library
Medium
Photograph
Description
Migraine therapy and CGRP receptor, illustration. Monoclonal antibodies (red) being used to block the calcitonin gene-related peptide (CGRP) receptor (blue). The calcitonin gene-related peptide (CGRP, yellow) is designed to bind to its receptor (blue). This occurs on the membranes of neurons and smooth muscle cells in cerebral (brain) blood vessels, activating a signal cascade through G-proteins (dark blue, bottom) that leads to a dilatation of brain blood vessels (vasodilatation). This is a factor in disorders such as migraines. Blocking the CGRP receptor reduces the number of migraine attacks.
Uploaded
October 24th, 2019
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